Lignans and Mesothelioma: A Comprehensive Review : mesothelioma.id administrator, Mei 3, 2023 Mesothelioma is a type of cancer that affects the lining of the lungs, abdomen, and chest. Asbestos exposure is the primary cause of this disease, which is challenging to diagnose and treat. In recent years, researchers have shown interest in the use of lignans in the treatment of mesothelioma. In this journal article, we will explore the therapeutic potential of lignans and their effect on mesothelioma. Here’s what you’ll find in this article: Baca Cepat show Table of Contents 1. What are lignans? 1.1 Types of lignans 1.2 Sources of lignans 2. How do lignans affect cancer cells? 3. Mesothelioma: An overview 3.1 Types of mesothelioma 3.2 Stages of mesothelioma 4. Causes and symptoms of mesothelioma 5. Diagnosis of mesothelioma 6. Treatment options for mesothelioma 7. Why lignans are essential in mesothelioma treatment? 8. Types of lignans used in mesothelioma treatment 8.1 SDG 8.2 Matairesinol 9. Benefits of lignans in mesothelioma treatment 10. Studies on lignans and mesothelioma 11. Lignans as a complementary treatment for mesothelioma 12. Side effects of lignans in mesothelioma treatment 13. Precautions to take when using lignans for mesothelioma treatment 14. FAQs about lignans and mesothelioma 14.1 Can lignans cure mesothelioma? 14.2 Are lignans safe to use? 14.3 What are the benefits of using lignans in mesothelioma treatment? 14.4 What precautions should I take when using lignans for mesothelioma treatment? 14.5 Can lignans be used alongside chemotherapy and radiation therapy? 14.6 Are there any food sources of lignans? Conclusion Source : Table of Contents What are lignans? How do lignans affect cancer cells? Mesothelioma: An overview Causes and symptoms of mesothelioma Diagnosis of mesothelioma Treatment options for mesothelioma Why lignans are essential in mesothelioma treatment? Types of lignans used in mesothelioma treatment Benefits of lignans in mesothelioma treatment Studies on lignans and mesothelioma Lignans as a complementary treatment for mesothelioma Side effects of lignans in mesothelioma treatment Precautions to take when using lignans for mesothelioma treatment FAQs about lignans and mesothelioma 1. What are lignans? Lignans are a type of polyphenolic compound found in plants. They are commonly found in flaxseed, sesame seeds, legumes, and whole grains. Lignans are known for their antioxidant and anti-inflammatory properties, making them effective in treating various diseases, including cancer. 1.1 Types of lignans There are two primary types of lignans, namely secoisolariciresinol diglucoside (SDG) and matairesinol. SDG is found primarily in flaxseed, while matairesinol is found in sesame seeds and legumes. 1.2 Sources of lignans Lignans are found in various plant-based foods, such as: Flaxseed Sesame seeds Legumes Whole grains Veggies like broccoli, kale, and carrots Fruits like strawberries, peaches, and blackberries 2. How do lignans affect cancer cells? Lignans have shown promise in the treatment of various cancers, including breast, prostate, and colon cancer. Lignans act as phytoestrogens, which means they can bind to estrogen receptors in the body. Estrogen plays a significant role in the growth and development of breast cancer cells. Lignans can help reduce the levels of estrogen in the body and reduce the risk of breast cancer. Lignans also have anti-inflammatory and antioxidant properties, making them effective in preventing the growth and spread of cancer cells. They can help lower the risk of cancer by protecting the body from oxidative stress. 3. Mesothelioma: An overview Mesothelioma is a type of cancer that affects the lining of the lungs, chest, and abdomen. It is caused by exposure to asbestos fibers, which can be inhaled or swallowed. Mesothelioma is a challenging disease to diagnose and treat, and it can take years for symptoms to appear. 3.1 Types of mesothelioma There are three primary types of mesothelioma, namely: Pleural mesothelioma Peritoneal mesothelioma Pericardial mesothelioma 3.2 Stages of mesothelioma Mesothelioma is classified into four stages, with stage 1 being the earliest and stage 4 being the most advanced. Early detection is crucial in the treatment of mesothelioma, and patients’ chances of survival are higher if the disease is caught in its earliest stages. 4. Causes and symptoms of mesothelioma Mesothelioma is caused primarily by exposure to asbestos fibers. Other risk factors include: Age Gender Smoking Family history of cancer Symptoms of mesothelioma may include: Chest pain Shortness of breath Fatigue Coughing Fever Night sweats 5. Diagnosis of mesothelioma Diagnosing mesothelioma is often challenging, as its early symptoms can mimic those of other respiratory diseases. Some tests that may be used in diagnosing mesothelioma include: Chest X-ray CT scan MRI scan PET scan Biopsy 6. Treatment options for mesothelioma Treatment options for mesothelioma depend on the stage and type of the disease. Some of the treatment options available include: Surgery Chemotherapy Radiation therapy Immunotherapy Multimodal therapy 7. Why lignans are essential in mesothelioma treatment? Lignans have anti-cancer properties that make them an effective complementary treatment for mesothelioma. They can help slow down the growth and spread of cancer cells while minimizing the risk of side effects that come with traditional treatments like chemotherapy and radiation. 8. Types of lignans used in mesothelioma treatment The two primary types of lignans used in mesothelioma treatment are secoisolariciresinol diglucoside (SDG) and matairesinol. 8.1 SDG SDG is found primarily in flaxseed and has shown promise in the treatment of breast and prostate cancer. It is also effective in preventing the growth and spread of mesothelioma cells. SDG can help improve the effectiveness of chemotherapy and radiation therapy. 8.2 Matairesinol Matairesinol is found in sesame seeds and legumes and has shown promise in the treatment of various cancers, including breast and prostate cancer. It can also help reduce the risk of mesothelioma by protecting the body from oxidative stress. 9. Benefits of lignans in mesothelioma treatment Lignans have several benefits when used in mesothelioma treatment, including: Reduced risk of side effects associated with traditional treatments Improved effectiveness of chemotherapy and radiation therapy Slowed growth and spread of cancer cells Protection against oxidative stress and inflammation 10. Studies on lignans and mesothelioma Several studies have been conducted on the use of lignans in mesothelioma treatment. One study found that flaxseed lignans could help slow down the growth and spread of mesothelioma cells. Another study found that SDG could improve the effectiveness of chemotherapy in treating mesothelioma. 11. Lignans as a complementary treatment for mesothelioma Lignans can be used as a complementary treatment for mesothelioma. They can help reduce the risk of side effects associated with traditional treatments while improving their effectiveness. 12. Side effects of lignans in mesothelioma treatment Lignans are generally safe to use, and they have few side effects. However, some people may experience gastrointestinal side effects, such as diarrhea and constipation. 13. Precautions to take when using lignans for mesothelioma treatment It is essential to consult with a healthcare provider before using lignans for mesothelioma treatment. They can provide guidance on the appropriate dosage and any possible drug interactions. 14. FAQs about lignans and mesothelioma 14.1 Can lignans cure mesothelioma? No, lignans cannot cure mesothelioma, but they can be used as complementary treatment to slow down the growth and spread of cancer cells. 14.2 Are lignans safe to use? Yes, lignans are generally safe to use, and they have few side effects. However, it is essential to consult with a healthcare provider before using them. 14.3 What are the benefits of using lignans in mesothelioma treatment? Lignans can help reduce the risk of side effects associated with traditional treatments while improving their effectiveness. They can also slow down the growth and spread of cancer cells. 14.4 What precautions should I take when using lignans for mesothelioma treatment? It is essential to consult with a healthcare provider before using lignans for mesothelioma treatment. They can provide guidance on the appropriate dosage and any possible drug interactions. 14.5 Can lignans be used alongside chemotherapy and radiation therapy? Yes, lignans can be used alongside chemotherapy and radiation therapy. They can help improve the effectiveness of these treatments while minimizing the risk of side effects. 14.6 Are there any food sources of lignans? Yes, lignans are found in various plant-based foods, such as flaxseed, sesame seeds, legumes, whole grains, and vegetables like broccoli, kale, and carrots. Conclusion Lignans have shown promise in the treatment of mesothelioma. They have anti-cancer properties that make them an effective complementary treatment for traditional therapies like chemotherapy and radiation. However, it is essential to consult with a healthcare provider before using lignans for mesothelioma treatment. They can provide guidance on the appropriate dosage and any possible drug interactions. Source : mesothelioma.id lignans and mesothelioma Berita Umum